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COVID-19 VACCINATION:
STATUS QUO
A STATISTA DOSSIERPLUS ON THE COVID-19 VACCINES AND THE
ONGOING VACCINATION CAMPAIGNS. LAST UPDATE:
APRIL 29, 2021
The COVID-19 pandemic: one year later
Timeline of the pandemic
Reduced mobility
The COVID-19 vaccines
SARS-CoV-2 mutations
Table of contents
Vaccination strategies
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Acceptance of the COVID-19 vaccine
The vaccination campaign: status
quo
United States
Largest EU member states (Germany,
France, Italy)
United Kingdom
Conclusion and outlook04
Started in late 2020, the vaccination campaigns are feeding the
hope for the pandemic to lose momentum in 2021
The spread of the SARS-CoV-2 virus, responsible for the COVID-19
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mode. One year after the first cases of COVID-19 were recorded in
China, the pandemic totaled, as of April 2021, 149.6 million infections
and 3.2 million casualties worldwide in official records. Similar tothe
influenza virus, the spread of SARS-CoV-2 has been occurring in waves.
During phases of peak contagion, national health systems were put
under enormous sometimes even unbearable pressure. This
compelled the national governments to find strategies to reduce the
spread of the virus.
Since the beginning of the pandemic, the curtailment of SARS-CoV-2 has
been attainable only through mobility-reducing measures (lockdowns),
social distancing, and increased hygiene standards (e.g., wide usage of
face masks). Vaccines are now offering hope to deescalate the
pandemic without these strict measures.As early as summer 2020,
some potential vaccines cleared the rigid testing and licensure
processes of national and international health authorities, a step which
offered the concrete possibility of reaching a generalized immunity
against COVID-19 and bringing the pandemic to an end. Whereas the
development of multiple safe, effective, and protocol-compliant
vaccines within one year is already an unprecedented achievement in
the history of vaccines, producing, distributing, and administering them
on a global scale also presents complex challenges. Moreover, eleven
on the 12 vaccines currently in use and the majority of those in the
latest stage of testing require two injections to be fully effective, thus
doubling the number of needed resources.
As of April 2021, the mass vaccination campaigns have started in most
partsof the world, targeting to attain herd immunity against COVID-19
perhaps within 2021. In terms of sheer numbers, this translates to
administering a vaccine twice per patient in a little more than 365 days
to, at least, 70 percent of the population. Focusing on the United States
and large European countries (Germany, United Kingdom, France, and
Italy), Statista is tracking the number of COVID-19 vaccines issued per
day and comparing these figures with the average numbers needed for
reaching herd immunity by the 31st of December 2021. As of April 2021,
all the abovementioned countries appear to have reached the critical
number of average daily vaccinations in order to achieve herd immunity
against SARS-CoV-2 by the end of 2021.
Executive summary
The COVID-19 pandemic: one year
later
Timeline of the pandemic
Reduced mobility
The COVID-19 vaccines
SARS-CoV-2 mutations
One year after SARS-CoV-2 was first identified in Hubei, China, its
pandemic spread has triggered a global race for the vaccine
Overview
First detected in the Chinese province of Hubei between the end of 2019 and
January 2020, the novel SARS-CoV-2 virus, responsible for the COVID-19
disease, rapidly reached a pandemic spread. From China's cancellation of the
events related to the Lunar New Year, planned for the last weekend of January
2020, to the WHO statement officially declaring the spread of the SARS-CoV-2
pandemic, less than 50 days passed.The spread of the virus, already in the so-
called first wave of January-May 2020, was confirmed to be a serious threat for
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including those of the most advanced countries.
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that the population was asked (or, in some countries, ordered) to reduce time
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spread. The second was that the pharmaceutical industry andresearch
facilities began research into developing more effective medicine and, most
importantly, a vaccine. Despite not having any precedent in the modern history
of medicine, one year later, over 300 candidate vaccines against SARS-CoV-2
have been submitted to the various health authorities for approval. Of these,
12 were officially approved and are currently being administered to a wide
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Note(s): *intended as vaccines approved by at least one national health authority in the world and widely administered to the population (outside a testing scheme)
Source(s): John Hopkins University, WHO, Statista
The pandemic in numbers
(as of xx.02.2020)
Certified infections worldwide
Certified casualties worldwide
Vaccines undergoing testing and
approval process
Vaccines currently in use*
The pandemic in number as of April 29, 2021
149.6 million
3.2 million
> 300
COVID-19 has infected over 149.6 million people and caused 3.2
million deaths so far; now it's gaining momentum
COVID-19 cumulative infections (left axis) and casualties (right axis), as of April 29, 2021
Source(s): ABC news,Johns Hopkins University, Statista
100
120
140
160
January 2020February 2020
March 2020April 2020May 2020June 2020July 2020
August 2020
September 2020
October 2020
November 2020December 2020
January 2021February 2021
March 2021April 2021
COVID
-19 reported cumulative casualties worldwide,
in millions
COVID
-19 reported cumulative infections worldwide,
in millions
Cumulative infectionsCumulative casualties
January 25, 2020:
China cancelsLunar
New Year celebrations
February 5, 2020:
Diamond Princess
cruise ship
quarantined
March 11, 2020:
WHO declares the
spread of SARS-CoV-2
pandemic
May 27, 2020:
100,000 COVID-19
victims in the U.S.
August 11, 2020:
Sputnik V vaccine
approved in Russia
December 27, 2020:
Vaccine day in the
European Union
April 2, 2021:
100 million people
received at least one
dose of COVID-19
vaccine in the United
States
January
February
March
April
May
June
July
August
September
October
November
December
January
February
March
April
4681012141618202224262830323436384042444648505213579111315
The spread of SARS-CoV-2 took place in waves;the highest
numbers wererecorded in December 2020 and January 2021
COVID-19 daily cases, selected countries and aggregated by calendar week
Source(s): Johns Hopkins University, Statista
200,000
400,000
600,000
800,000
1,000,000
1,200,000
1,400,000
1,600,000
1,800,000
2,000,000
4681012141618202224262830323436384042444648505213579111315
United StatesGermanyUnited KingdomFranceItaly2020
COVID
-19 new confirmed cases, weekly2021
The widening spread of SARS-CoV-2 in
March 2020, first in Europe and in the
United States shortly afterwards, made it
necessary for these countries to introduce
measures to reduce the mobility of their
citizens.
The strategy of national lockdowns included
the temporary closures of public spaces
(schools, universities) and recreational
spaces (restaurants, cinemas, theaters,
sports facilities) and required employers to
facilitate working from home for those
employees that could do so.
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increased both within March and May 2020
(first wave), and again from October 2020
onward (second wave). The time spent in
the workplace was inversely proportional,
declining the most during the peaks of the
two waves.
The most common solution to reduce the spread of SARS-CoV-2 was
to ask people to reduce their mobility and stay home
Note(s): *Defined as the days between January 3, 2020 and February 6, 2020.
Source(s): Google mobility trends, our world in data
Google mobility trends, selected countries
-80%
-60%
-40%
-20%
20%
40%
60%
80%
89101112131415161718192021222324252627282930313233343536373839404142434445464748495051525312345678910111213141516
United StatesGermanyUnited KingdomFranceItaly
Residential
Workplace
Mar.Apr.MayJun.Jul.Aug.Sep.Oct.Nov.Dec.Jan. 2021
Percentage change compared to pre
-pandemic period*, weekly
Feb.Mar.Apr.MayJun.Jul.Aug.Sep.Oct.Nov.Dec.Jan. 2021Feb.Mar.Apr.
Development and licensure of a newly developed vaccine, United States regulations
Developing vaccines for COVID-19 became pivotal, yet adhering to
official protocols to ensure safety and efficacy is crucial
Exploratory
stage
Pre-clinical
stage
IND
application
Phase I trials
Phase II
trials
Phase III
trials
Approval
and
licensure
Post-
licensure
monitoring
Basic
laboratory
research.
Human
cellculture
and/or animal
testing.
Application to the
U.S. Food and
Drug
Administration.
Tests on a small group of adults
(20 to 80 subjects).
Focus on safety and extent of
immune response.
Tests on larger samples of
individuals, including risk groups.
Focus on immunogenicity,
proposed dose, and method of
delivery.
Larger scale tests,
involving 1,000 to
>10,000
individuals.
Submission of the
Biologics License
Application to the
U.S. Food and Drug
Administration.
Post-distribution
monitoring.
Focus on adverse
events.
Source(s): historyofvaccines.org, The New York Times
Vaccines currently in use
Source(s): London School of Hygiene & Tropical Medicine, WHO
COVID-19 vaccines in the latest stage of testing and in use, as of April 13, 2021
Within the year 2020, 304 candidate COVID-19 vaccines have been
developed; 12 of them are already in use
ManufacturerCountry of originCountries where the vaccine is used
Pfizer/BioNTechU.S./GermanyWHO countries
AstraZeneca/OxfordUKUK, EU, India, Argentina, Dominican Republic, El
Salvador, Mexico, Morocco
GamelayaResearch Inst.
(Sputnik V)RussiaRussia, Belarus, Argentina, Serbia, Paraguay,
Palestine
ModernaU.S.U.S., Canada, EU, Israel, UK, Switzerland
Anhui ZhifeiChinaChina
SinopharmChinaChina, UAE , Bahrain, Egypt, Hungary
SinovacChinaChina, Azerbaijan, Brazil, Chile, and Colombia
CanSino ChinaChina, Mexico, Pakistan
Wuhan/SinopharmChinaChina, UAE
Vector institute
(EpiVacCorona)RussiaRussia
BharatIndiaIndia (emergency use)
Johnson & JohnsonU.S.U.S., EU, Bahrain, South Africa
Phase III testingBef. Phase III
282vaccines
11 vaccines
Vaccines currently in use
12 vaccines
study id86257 covid19 vaccination status quo
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